Currently, there is primary and obligatory requirement to identify and introduce new and effective plants for producing natural antibiotics with high biological potentials and low side effects [1]. Phytobiotics are compounds of plant origin, which can be replaced like probiotics and prebiotics with growth promoter antibiotics. The main motivations to use the medicinal plants as growth promoters in poultry feed include anti-bacterial property, antioxidant activity, stimulation of appetite, increase the secretion of digestive enzymes, and boost the immune system. Of years away, the effective compounds in plants have been used to prevent types of bacteria and fungi [2]. Harmala with the scientific name of Peganum harmala is a perennial and non fluff plant from the family of Nitrariaceae. Seeds from this plant are rich in carbohydrates, lipids, proteins, minerals, alkaloids and amino acids. Alkaloids are the active compounds of harmala which also known as Beta-Carbolines, and accumulate in parts of the seeds and roots of the plant. They include Harman, Norharman, Harmine, Harmalol, Harmaline, Vasyzin and Vasyzinun. It has been reported that the addition of 250 mg/lit of harmala extract to drinking water improved body weight gain and feed conversion ratio in broilers, but had no effect on feed intake [3]. In this study, 288 one-day old Ross 308 broiler chicks were randomly assigned to 4 treatments and 4 replication of 18 birds in each per treatment. The experimental treatments were control (with no feed additive), 0.02% Virginiamycin as growth promoter antibiotic, 0.25% harmala seed powder and 0.50% harmala seed powder. Feed intake, body weight, body weight gain, and feed conversion ratio (FCR) was recorded weekly. The data were analyzed in a completely randomized design using GLM procedure of SAS. Comparison of means was conducted by Duncan's multiple range rest. The results of this study showed that 0.50% dietary harmala seed powder significantly (P<0.05) reduced feed
