Covalent organic frameworks (COFs), constructed by organic building blocks, to make two and three dimensional geometry and are assembled with light elements (such as B, N, C, O) that are connected via strong covalent bonds [1]. On the other hand, N-heterocyclic compounds as important classes of natural and synthetics organic materials, have numerous biological activities [2]. Among N-heterocyclic compounds, 1,5-dihydro-2H-pyrrol-2-ones assuredly have considerable potential application in pharmaceutical industries and bioactive natural products owing to their notable biological properties such as anti-cancer, anti-tumor, anti-biotic and anti-diabetic [3]. In this study, we synthesized 1,5-dihydro-2H-pyrrol-2-one derivatives via multicomponent cyclo-condensation reaction of aldehydes, aryl amines and ethyl pyruvate as starting materials by using COF-SO3H as heterogeneous active catalyst under mild reaction condition with excellent yields (Scheme 1). The synthesized pyrrol-2-one derivatives were characterized by using FT-IR and NMR analyses.
