In recent years, the synthesis of metal-organic frameworks (MOFs) as a new generation of nanoreactors has expanded significantly. MOFs are crystalline structures with tunable pores, the attractive scientific properties of this class of porous materials have attracted much scientific attention. Nowadays, MOFs have wide applications in various fields such as catalysts, photocatalysts, energy storage, gas absorption and sensors [1]. Catalytic applications of MOFs have created an interesting research motive due to the high porosity, high surface area, chemical and thermal stability of these compounds. In this context, the placement of ionic liquids that have low volatility, high thermal stability, low vapor pressure and are environmentally friendly in the pores of MOFs has caused interesting physical and chemical properties in MOFs [2]. With these attractive features in mind, we have developed the highly motivated [Zr-UiO-66-imidazole]Br, a Catalyst Ionic Liquid Metal Organic Frameworks (ILMOFs). The catalytic application of the above ILMOFs was measured in the preparation of a wide range of macromolecule compounds which mainly have significant biological properties such as anti-cancer, anti-tumor, and anti-bacterial properties
