Metal-Organic Frameworks (MOFs) are porous compounds with high design capability and controllable properties, which have been interesting research fields in recent decades. MOFs, which are also called porous coordination polymers (PCP), are obtained by covalently connecting metal clusters to organic ligands and creating a crystalline structure [1]. The broad features of MOFs, including high thermal stability, high porosity, crystalline nature, and adjustable pores, have caused these platforms ideal chemical to be used in various fields such as gas storage, targeted drug delivery, absorption, desorption, sensors, photo catalysts, and catalysts [2]. In recent years, increasing the stability of MOFs has been of great interest. An attractive perspective for this is the integration of MOFs with metallic nanoparticles (NPs). the integration of Fe3O4 and MOFs has been able to create compounds with interesting properties. Magnetic metal-organic frameworks (MMOFs) have wide applications in various fields such as drug delivery, catalyst, photocatalyst, separation, positioning and absorption of chemical compounds. Recent scientists pay special attention to the preparation of compounds with biological and medicinal properties. Among them, pyrazolo[3,4-b]pyridine are of interest with biological properties such as anti-cancer, anti-bacterial, anti-fungal and anti-parasitic.