Nowadays, metal-organic frameworks (MOFs), are known as new generation nanoreactors. These compounds are formed as porous coordinated polymers by connecting metals and organic ligands. Drug delivery, energy and gas storage, chemical and biological sensor, water purification, catalyst and photocatalyst are applications of MOFs. Recently, the use of metalorganic frameworks (MOFs) containing two metals has found wide application which are known as bimetallic-MOFs. Studies have shown that in this category of catalysts, the two metals present in the MOF structure cause a synergistic effect [1]. In recent years, the use of heterogeneous catalysts modified with organic compounds such as urea and thiourea as hydrogen-bonding catalysts has become widespread. Catalysts based on hydrogen bonding have high selectivity and this ability has improved their catalytic properties because in this case they can play both an acidic and a basic role [2]. Pyrazolo[3,4-b]quinolines have been found to exhibit a wide range of biological activities, including antitumor, antiviral, and antiinflammatory properties [3]. Considering the mentioned characteristics, we became interested in the synthesis of this group of compounds with the help of a new generation of hydrogen bond catalysts based on metal-organic frameworks (MOFs). Among the features of the above work is easy synthesis, high efficiency of products, reduction of side products and the ability to recycle the catalyst.
