2025 : 4 : 22

ma z

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
HIndex:
Faculty: Faculty of Chemistry and Petroleum Sciences
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Research

Title
Transition metal‑free synthesis of quinolino[2′,3′:3,4] pyrazolo[5,1‑b]quinazolin‑8(6H)‑ones via cascade dehydrogenation and intramolecular N‑arylation
Type
JournalPaper
Keywords
Quinoline · Quinazolinone · Intramolecular N-arylation · Cascade reaction · Polyheterocycles · Transition metal-free
Year
2016
Journal Journal of the Iranian Chemical Society
DOI
Researchers First-Name Last-Name ، Majid Heravi ، Hoda Hamidi ، ma z ، ، Atefeh Nejatnejad ، Suhash Shintre ، Neil Koorbanally

Abstract

2-(2-Chloroquinolin-3-yl)-3-(arylamino)- 2,3-dihydroquinazolin-4(1H)-one was converted to quinolino[ 2′,3′:3,4]pyrazolo[5,1-b]quinazolin-8(6H)-ones in the presence of KOtBu in DMSO at room temperature. The present method has the advantages of easy conditions, construction of highly novel five heterocycles, transition metalfree conditions, cascade dehydrogenation and intramolecular N-arylation and good to high yield of products