Pyridine scaffolds as the most important families of nitrogen-containing heterocycles, have wide spread applications in natural products, pharmaceuticals, supramolecular chemistry, molecular machines, catalytic applications and functional materials [1-3]. These systems, due to privileged characteristics in medicinal chemistry have a tremendous application such as antiasthmatic, preventing or inducing apoptosis, antidepressant and inhibiting HIV protease. [4-5] Recently, terpyridines as the preeminent subset of pyridine derivatives have found extraordinary application in modern chemistry. Undoubtedly, these compounds are the most important category in coordination chemistry [6-7]. There are many applications for terpyridine families such as cancer therapy [8], self-healing materials [9], catalytic applications [10], chemical probes [11] and chemical sensors [12]. In this study, ammonium acetate was used as a catalytically active reagent for the synthesis of novel di indolyl terpyridines via cooperative vinylogous anomeric-based oxidation (Scheme 1).
