A novel acidic nanocatalytic system, sulfamic acid-functionalized Fe3-xTixO4 magnetic nanoparticles (MNPs), were synthesized through one-pot reaction of Fe3-xTixO4 MNPs with 3-chloropropyltrimethoxysilane and imidazolidine-2,4-dione followed by functionalization with chlorosulfonic acid. The structure of this newly synthesized nanocatalyst was established by several analysis methods including, Fourier-transform infrared (FTIR) and energy-dispersive X-ray (EDX) spectroscopies, transmission (TEM) and scanning (SEM) electron microscopies, thermal gravimetric (TG), X-ray diffraction (XRD), and vibrating sample magnetometer (VSM). The potential catalytic ability of this nanocatalyst was evaluated in one-pot four-component condensation reaction between aromatic aldehydes, dimedone, alkyl acetoacetates and ammonium acetate in order to synthesis of hexahydroquinoline derivatives. The reactions proceeded smoothly under solvent-free condition offering excellent yields of corresponding hexahydroquinolines successfully. In addition, the fabricated nanocatalyst exhibited excellent reusability up to four subsequent runs.
