tIn this investigation, isophthalate derivatives were prepared by the reaction of isophthaloyl dichloridewith various alcohol derivatives using ZrOCl2as an efficient, green and a heterogeneous catalyst undermicrowave irradiation and solvent- free condition. Optimization of the reaction condition was studiedby the response surface method (Box Behnken Design (BBD)) with three replicates at a central point fordeveloping a second order model. Predicting response values using the obtained model were in a goodaccordance with the experimental results. Clean reaction, easy workup procedure, the reusability of thecatalyst, short reaction times and high yields were some advantages of this work.
