محمدعلی زلفی گل

In recent years, the use of ionic liquids and solid salts as homogeneous, heterogeneous and reusable catalysts has received massive attention in organic synthesis.1 Pyranopyrazoles are an important class of heterocyclic compounds. They have been used as fungicidal,2 bactericidal, vasodilatory,3 and anti-cancer.4 These heterocycles have also applications such as pharmaceutical ingredients and biodegradable5 agrochemicals. In this investigation, we report a highly efficient solvent-free method for the synthesis of 6-amino-4-(4- methoxyphenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles by the onepot multi-component condensation of arylaldehydes with ethyl acetoacetate, malononitrile and hydrazine hydrate using acetic acid functionalized ionic liquid as heterogeneous catalyst