محمدعلی زلفی گل

The purpose of science and technology has been shifting toward more environment friendly, tolerable sources and reusable catalysts to minimize waste. Thus, the development of functionalized magnetic nanoparticles as noteworthy candidates in the search for supporting of catalysts is currently a subject of increasing interest due to easily separated and recycled from the products by an external magnet.1-3 Among the various heterocyclic compounds used in medicinal chemistry, the indole moiety has a long tradition of biologically relevant compounds, and hence, their synthesis and functionalization have been extensively investigated.4,5 Herein, we report prepare novel magnetic catalyst thiourea dioxide (TUD)- SO3H supported on Fe3O4/silica-coated for the synthesis of 1,1,3-tri heteroaryl compounds via mixed Michael and Friedel–Crafts reactions. Methods used for this synthesis is simple and clean. Also used catalyst has high catalytic power and reusable (Scheme 1). The scope and limitation of the described procedure will be presented