Background: Unemployed individuals have lower psychological and physical well-being than did their employed counterparts , the possibility of their tendency to drug abuse and injecting it also does more. Thus, The aim of this study was to determine mental disorders among Unemployed people and the employed at the start of injection. Methods: Study method was cross- sectional. Research statistics universe constitutes of all People suffering substance dependence disorder in Tehran and Hamedan city. The sample consisted of 235 individual with substance dependence disorder, that selected from harm reduction centers in Tehran and Hamedan city, The sampling selection method was simple random. We used the SCL90-R questionnaire to evaluate psychological disorders and A demographic questionnaire among in injection drug users. Results: Results Analysis of Independent t showed that at the start of injection drug-dependent persons, the average mental disorders such as somatization disorder, depression, anxiety disorder, anxiety disorder, interpersonal sensitivity, paranoid disorder and psychotic symptoms was higher in Unemployed persons than those who were employed. Conclusions: The findings suggest that Mental disorders, unemployment and injection drug use have communications chain, so interventionist policy should be to improve the socio-economic and psychological conditions as comprehensive and at the same time.
