So far, the communication standard development requires specific parameters to achieve the requests of the desired application, most frequently, the connection speed rate. On the other hand, the term Beyond the Fifth Generation (B5G) symbolizes certain specifications required to succeed the future-proof of the Fifth Generation (5G), i. e., the predicted high-level parameters, such as Ultra-reliable low-latency communications, massive machine-type communications, and improved mobile broadband, which are essential for the expected high-level future applications; consequently, 5G wireless (cellular) networks must be reconsidered precisely and in-depth to cope with the applications' required high-level standard parameters in B5G. As a result, developing new wireless access topologies and technologies utilizing extra spectrum is deemed significant; though it is yet insufficient. Software-defined networking, network function virtualization, machine learning, 3D networking, and cloud computing are among the technologies that are in need be integrated into B5G networks; taking into account that decentralization, transparency, interoperability, privacy, and security are all issues raised by these technologies. This paper provides a comprehensive overview of B5G technology and its relation to the cloud computing, including details on B5G and its infrastructure, features and security. Moreover, the proposed research investigates the communication of B5G applications, such as Vehicle to Vehicular (V2V), Device-to-Device (D2D), and Machine-to-Machine (M2M). Finally, the proposed study focuses on crucial emerging software services that benefit from the advantages of B5G communication systems and cloud computing, such as health, Smart Grid, Tourism, and agriculture services.