Process intensification of liquid–liquid extraction based on single drop studies is discussed. Design, sim-ulation and optimization of this process, usually adopts with swarm of drops, and depends on individualdrops behavior as well as the relevant influential parameters. Improving mass transfer performance withoptimized operating conditions or using additives like salts and nanoparticles are distinctive concerns.Accordingly, as a systematic study, the hydrodynamic and mass transfer behavior of drops as well aseffects of operating parameters are considered. Due to the importance of subject, the behavior ofnanoparticles for improving extraction process, with or without external fields, is highly regarded.Furthermore, the promising techniques/materials of reactive extraction, microfluidic extraction, ionic liq-uid solvents, their combination and coupling heat and mass transfer are considered. The content will bringgreater clarity to select additives and to employ suitable conditions. Indeed, drop intensification methods,in relation to the drop breakage/coalescence, build the high performance industrial scale operations.
