cardio-metabolic diseases, including diabetes, hypertension, dyslipidemia, and coronary heart disease (CHD). Specially, greater physical activity is known to prevent and reduce the risk of many cardio-metabolic diseases. Walking is used under lifestyle conditions as a movement current pattern, especially in several social jobs. The aim of present study is to evaluate the relationship step per day with cardio-metabolic risk factors , and the effects of physical activity volume on this variables. Methods: daily step volumes voluntarily were measured in the health postmenopausal women(n=40) by the electronic pedometer. Subjects (aged 55.9 ±4.6) divided by as active group(AG =20) and sedentary group(SG=20). Cardio-metabolic variables analyzed with the standards methods. Results: Daily step averages in the AG(8022±2659 step/day) significantly was higher than SG (3450±913 step/day) (p<0.001). ). There was a significant difference in body composition variables (BMI,%BF, WHR) among 2 groups and significant inverse correlations were found between activity and body composition variables in women(p<0.05). The significant inverse correlations was found between activity and HDL-C(r=0.34). the other correlations (LDL-C,TC, TG, HOMA-IR,Insulin, blood sugar) with steps per day were not significant(p>0.05). Conclusion: In conclusion , in view of regular physical activity, increasing daily step volume may be associated with decrease risk factors for chronic disease (Increasing HDL-C) and obesity(BMI,%BF, WHR) for a 2 years period in the adult women. It seems that increasing steps per day (at least 8000 step/day) were not associated with changes in appetite hormones concentrations.
