Metal-organic frameworks (MOFs), are a class of functional meso-/micro-porous crystalline materials constituted by the auto-assemblage of metal ions or metal oxide clusters and organic ligands through covalent connection [1]. In all reported MOFs, the Zr-MOFs stand out due to the strong Zr-O coordination bond, practicable synthetic conditions, and facility of reproducibility. The strong Zr-O coordination bond, along with the robust polynuclear molecular building blocks, cause Zr-MOFs an exceptional family of structures that are promising because of their tenability, stability, and design ability [2]. Chromeno- quinolines show remarkable properties in biological, medicinal, and fluorescence areas [3]. A new Zr-MOF was synthesized based on zirconium cations, an amine-functionalized ligand, and a linear exo-bidentate bis-pyridine ligand. Then, catalytic application of the synthesized Zr-based MOF was successfully explored in the synthesis of 6H-chromeno[4,3- b]quinolin-6-ones via a one-pot three-component condensation reaction under solvent-free conditions at 110 °C
