In this research, palladium nanoparticles (Pd NPs) were first synthesized using laser ablation in the deionized (DI) water environment. Also, metal-organic framework (MOF) was produced using the solvothermal method at a temperature of 150°C. To accumulate Pd NPs on the synthesized MOF, ultrasonic and magnetic stirring methods were used. Different analytical methods were used to investigate the structure and morphology of the synthesized nanocomposite. Also, the sensitivity of the synthesized nanocomposite to ethanol and methanol organic vapors was investigated. The results showed an increase in the response of the MOF in the presence of nanoparticles.