Nepeta crispa Willd. is a species of Belongs to Nepeta genus. This genus is found in west and southwestern Iran. Because of its pharmaceutical and aromatic properties, this species is known locally as “Mofarrah” meaning "Breezy" in Iran. The aim of this research is to determine the geographic distribution, habitat, population and biology of Nepeta crispa as native and endemic species in Iran. This research has been conducted in Hamadan province during 2015 and its related steps are still underway. Documentary and observation methods have been used to access the information. This means that identifying capabilities and limitations of the studied area was made during the research period through extensive field inspections and direct field observations. Through the period, using the map, Global Positioning System (GPS) and in some cases through afoot surveying or using car, the geographical location of relevant habitat was identified. The capability of the studied area was shown on the map. Alvand mountains area is part of the Zagros mountainous in the west of Iran. The rocky areas with sleep slopes, cliffs, caves, deep valleys are suitable for reproduction of different species of wild animals and passing the winter season. High mountains cause snow precipitation, which in turn is very effective to recharge the underground water table. Few studies have been carried out about antimicrobial activity of the essential oil of Nepeta crispa Willd. For example, Sonboli et al, investigated the antimicrobial activity of the essential oil of Nepeta crispa Willd. In mentioned research, the oil was obtained from the aerial parts of the Nepeta crispa Willd and was tested against seven gram-negative or gram-positive bacteria and four fungi. Their study and the results of the bioassays showed that the oil exhibited moderate to strong antibacterial activity against all the tested bacteria and strong activity against the fungi. The present study revealed that the essential oil of N. cr
