In this paper, we take the advantages of the optical properties of carbon dots (CDs) and a comproportionation reaction to introduce a CD-based fluorescence strategy for periodate determination. The carbon dot, as the fluorescent probe, was prepared according to the previously reported method with some modifications. The prepared CDs were then used to the determination of periodate ion based on the inner filter effect. To the best of our knowledge this report is the first survey to determine this oxyanion by CDs via inner filter effect. In order to acquire the best signal and the highest sensitivity, it is obligatory to optimize the effective parameters, consistently. In this assay, these parameters include pH (6.3), CD concentration (150 mg/L) and iodide concentration (12 mM). Under the optimized conditions, linear relationship between the periodate concentration and the fluorescence quenching was obtained in the range 0.160 -20.0 µM. The developed periodate sensor was found capable to detect periodate ion as low as 0.018 µM. The proposed method can distinguish between periodate and iodate. It is possible that this novel fluorescent sensor can be applied in the bioimaging field.
