Electrochemistry is an efficient and powerful tool for synthesis, mechanistic and ki-netic studies and thermodynamic evaluation of the electron transfer reactions. It is widely used for the synthesis of some new organic compounds due to their simple, accessible, and practical properties, in addition being consistent with the principles of of green chemistry. It is known that cyclic voltammetry is an available technique for consideration of electrochemical reactions that are coupled with chemical reac-tions. As an electroactive substance, acetaminophen has also attracted much interest. Acetaminophen is used worldwide for its analgesic and antipyretic properties [1]. Thiols, as one of the intercellular reducing agents, generally protect biological sys-tems against oxidative and inflammatory stress by serving as radical scavengers and/or cofactors for intracellular enzymatic anti-oxidation functions
