This work reports on the development of a method for determination of Cd(II) and Pb(II) in the presence of each other using resonance light scattering (RLS) technique. In this regard, cysteamine functionalized CdS hollow nanospheres were synthesized and used as a probe. The synthesized hollow nanospheres were fully characterized using SEM, TEM, XRD, DLS and FTIR measurements. By the aid of synchronous scanning of the excitation and emission monochromators of a conventional spectrofluorometer, RLS spectra of the synthesized nanospheres in the presence and absence of the investigated metal ions were studied, and enhancement effect of the investigated metal ions was observed. The results showed that under different optimized conditions, it is possible to determine the investigated metal ions in the presence of each other with detection limits of 9.0 and 10.0 mg L1 for Pb(II) and Cd(II), respectively. Furthermore, the real sample analysis results confirmed the method applicability for accurate analysis of real water samples.
