مشخصات پژوهش

صفحه نخست /Proximal ureteral ...
عنوان
Proximal ureteral reconstruction using renal capsule flap: a canine experimental model
نوع پژوهش مقاله چاپ‌شده
کلیدواژه‌ها
: canine ‹› fold ‹› reconstruction ‹› renal capsule ‹› ureter
چکیده
Introduction The aim of this article was to evaluate the effectiveness of using the renal capsule in ureteral reconstruction in a canine model. Material and methods Ten clinically healthy male adult dogs were used in this study. Dogs underwent ureteral reconstruction using a tube-shaped flap of the renal capsule. Results All but one animal (90%) survived till nephrectomy and thereafter. At 30 days after operation, the double-J stent was removed from the ureter, and at the 60th day, intravenous pyelography confirmed openness of the duct. The internal surface of the tunneled flap was coated with thick, folded urothelium. Maturing granulation tissue and angiogenesis as well as fiber producing fibroblasts were observed in the lamina propria. The presence of smooth muscle cells beneath the lamina propria indicated complete reconstitution of the damaged ureter. Conclusions The results showed that the autologous renal capsular flap provided a practical option for treating ureteral defects in dogs with an acceptable outcome. So, using the selfsame renal capsular tissue is a feasible method for restoration of the injured proximal ureter
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